Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. [electronic resource]
Producer: 20080324Description: 929-33 p. digitalISSN:- 1464-3405
- Carbazoles -- chemical synthesis
- Cell Cycle Proteins -- antagonists & inhibitors
- Checkpoint Kinase 1
- Combinatorial Chemistry Techniques
- Humans
- Molecular Structure
- Nuclear Proteins -- antagonists & inhibitors
- Protein Kinase Inhibitors -- chemical synthesis
- Protein Kinases -- metabolism
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Structure-Activity Relationship
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Publication Type: Journal Article
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