Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5. [electronic resource]
Producer: 20080515Description: 3742-50 p. digitalISSN:- 0006-4971
- Aniline Compounds -- agonists
- Antineoplastic Agents, Alkylating -- agonists
- Apoptosis -- drug effects
- Diterpenes -- agonists
- Drug Synergism
- Epoxy Compounds -- agonists
- Female
- Humans
- Imidazoles -- agonists
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Phenanthrenes -- agonists
- Piperazines -- agonists
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- agonists
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
- U937 Cells
- X-Linked Inhibitor of Apoptosis Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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