Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies. [electronic resource]
Producer: 20080424Description: 907-17 p. digitalISSN:- 0891-5849
- Animals
- Antineoplastic Agents -- therapeutic use
- Brain -- drug effects
- Buthionine Sulfoximine -- pharmacology
- Cells, Cultured
- Computer Simulation
- Curcumin -- therapeutic use
- Dopamine -- physiology
- Glutathione -- deficiency
- In Vitro Techniques
- Male
- Mice
- Mice, Inbred C57BL
- Mitochondria -- physiology
- Models, Theoretical
- Neurons -- drug effects
- Neuroprotective Agents -- therapeutic use
- Oxidative Stress -- drug effects
- Parkinson Disease -- drug therapy
- Rats
- Systems Biology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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