ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. [electronic resource]
Producer: 20080530Description: 6572-83 p. digitalISSN:- 0021-9258
- Animals
- Antineoplastic Agents -- adverse effects
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- genetics
- Cell Line, Transformed
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- Cisplatin -- adverse effects
- DNA Damage -- drug effects
- DNA-Binding Proteins -- genetics
- Gene Deletion
- Histones -- genetics
- Humans
- Kidney Diseases -- chemically induced
- Kidney Tubules, Proximal -- injuries
- Neoplasms -- complications
- Proteasome Endopeptidase Complex -- genetics
- Protein Kinases -- genetics
- Protein Serine-Threonine Kinases -- genetics
- Rats
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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