A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B. [electronic resource]
Producer: 20080317Description: 1429-42 p. digitalISSN:- 1098-5549
- Alanine -- metabolism
- Amino Acid Substitution
- Amino Acids -- metabolism
- Animals
- Carcinoma, Hepatocellular -- pathology
- Catalytic Domain
- Cell Line
- Cell Line, Tumor
- Cells, Cultured
- Cycloheximide -- pharmacology
- Embryo, Mammalian
- Eukaryotic Initiation Factor-2B -- analysis
- Fibroblasts -- metabolism
- Genes, Reporter
- Histidine -- metabolism
- Humans
- Jurkat Cells
- Kidney -- cytology
- Liver Neoplasms -- pathology
- Luciferases, Renilla -- analysis
- Mice
- Models, Biological
- Peptide Mapping
- Phosphorylation
- Protein Biosynthesis
- Protein Structure, Tertiary
- Protein Synthesis Inhibitors -- pharmacology
- Serine -- metabolism
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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