Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects. [electronic resource]
Producer: 20080505Description: 42-50 p. digitalISSN:- 0277-0008
- Adolescent
- Adult
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Chromatography, High Pressure Liquid
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP3A
- Cytochrome P-450 CYP3A Inhibitors
- Diarrhea -- chemically induced
- Dizziness -- chemically induced
- Drug Interactions
- Female
- Gastric Juice -- drug effects
- HIV Protease Inhibitors -- adverse effects
- Headache -- chemically induced
- Humans
- Hydrogen-Ion Concentration -- drug effects
- Male
- Metabolic Clearance Rate
- Middle Aged
- Mixed Function Oxygenases -- antagonists & inhibitors
- Nelfinavir -- adverse effects
- Omeprazole -- adverse effects
- Proton Pump Inhibitors -- adverse effects
- Syncope -- chemically induced
- Tablets
No physical items for this record
Publication Type: Journal Article; Randomized Controlled Trial
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