Kallikrein gene 'knock-down' by small interfering RNA transfection induces a profibrotic phenotype in rat mesangial cells. [electronic resource]
Producer: 20080828Description: 93-101 p. digitalISSN:- 0263-6352
- Animals
- Blotting, Western
- Cells, Cultured
- Culture Media, Conditioned -- pharmacology
- Dose-Response Relationship, Drug
- Female
- Fibronectins -- drug effects
- Fibrosis -- chemically induced
- Gene Expression Regulation, Enzymologic -- drug effects
- Low Density Lipoprotein Receptor-Related Protein-1 -- drug effects
- Male
- Matrix Metalloproteinase 2 -- drug effects
- Mesangial Cells -- drug effects
- Phenotype
- RNA, Messenger -- antagonists & inhibitors
- RNA, Small Interfering -- pharmacology
- Rats
- Rats, Wistar
- Receptor, Bradykinin B2 -- drug effects
- Tissue Kallikreins -- biosynthesis
- Transfection
- Transforming Growth Factor beta -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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