Disulfide bond disruption by a beta 3-Cys549Arg mutation in six Jordanian families with Glanzmann thrombasthenia causes diminished production of constitutively active alpha IIb beta 3. [electronic resource]
Producer: 20080226Description: 1257-65 p. digitalISSN:- 0340-6245
- Adult
- Amino Acid Sequence
- Animals
- Cell Line
- Cell Membrane -- metabolism
- Cricetinae
- Cysteine -- chemistry
- DNA Mutational Analysis
- Disulfides -- chemistry
- Family
- Female
- Founder Effect
- Genotype
- Haplotypes
- Homozygote
- Humans
- Integrin alpha2 -- blood
- Jordan
- Male
- Molecular Sequence Data
- Mutation
- Pedigree
- Phenotype
- Platelet Glycoprotein GPIIb-IIIa Complex -- chemistry
- Protein Conformation
- Protein Structure, Tertiary
- Sequence Alignment
- Severity of Illness Index
- Thrombasthenia -- blood
- Transfection
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.