ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells. [electronic resource]
Producer: 20080306Description: 250-63 p. digitalISSN:- 1460-2156
- Amides -- pharmacology
- Animals
- Cell Size -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Ciliary Neurotrophic Factor -- pharmacology
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Mitogen-Activated Protein Kinase Kinases -- physiology
- Nerve Crush
- Nerve Regeneration -- drug effects
- Neurites -- drug effects
- Optic Nerve -- physiology
- Proto-Oncogene Proteins c-akt -- physiology
- Pyridines -- pharmacology
- Rats
- Rats, Wistar
- Retina -- enzymology
- Retinal Ganglion Cells -- drug effects
- STAT3 Transcription Factor -- physiology
- Signal Transduction -- drug effects
- Up-Regulation
- rho-Associated Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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