Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. [electronic resource]
Producer: 20080107Description: 712-6 p. digitalISSN:- 1476-4687
- Acetylation
- Allosteric Site
- Animals
- Blood Glucose -- metabolism
- Caloric Restriction
- Catalytic Domain
- Cell Line
- Diabetes Mellitus, Type 2 -- drug therapy
- Dietary Fats -- administration & dosage
- Disease Models, Animal
- Drosophila melanogaster
- Heterocyclic Compounds, 4 or More Rings -- pharmacology
- Humans
- Insulin -- metabolism
- Male
- Mice
- Mitochondria -- drug effects
- Rats
- Rats, Sprague-Dawley
- Rats, Zucker
- Resveratrol
- Sirtuin 1
- Sirtuins -- agonists
- Stilbenes -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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