Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway. [electronic resource]
Producer: 20080508Description: 251-66 p. digitalISSN:- 1398-9219
- Acetylcysteine -- analogs & derivatives
- Animals
- CHO Cells
- Cell Communication -- physiology
- Cell Line, Tumor
- Cricetinae
- Cricetulus
- Endocytosis -- physiology
- Enzyme Inhibitors -- pharmacology
- Ephrin-B1 -- metabolism
- Humans
- Lysosomes -- drug effects
- Macrolides -- pharmacology
- Mice
- Models, Biological
- Mutation
- Phosphorylation -- drug effects
- Protein Binding
- Proto-Oncogene Proteins c-cbl -- genetics
- Pyrimidines -- pharmacology
- Receptor, EphB1 -- genetics
- Signal Transduction -- drug effects
- Transfection
- Ubiquitination -- drug effects
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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