RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes. [electronic resource]
Producer: 20080221Description: 92-104 p. digitalISSN:- 0270-4137
- Animals
- Bone Neoplasms -- genetics
- Cell Line, Tumor
- Cell Movement -- drug effects
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Male
- Mice
- Mice, SCID
- Neoplasm Transplantation
- Osteolysis -- pathology
- Osteoprotegerin -- pharmacology
- Prostatic Neoplasms -- genetics
- RANK Ligand -- antagonists & inhibitors
- RNA, Messenger -- metabolism
- Receptor Activator of Nuclear Factor-kappa B -- genetics
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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