Commercial peptidoglycan preparations are contaminated with superantigen-like activity that stimulates IL-17 production. [electronic resource]
Producer: 20080409Description: 409-18 p. digitalISSN:- 0741-5400
- Antigens, Bacterial -- analysis
- Artifacts
- Cell Line
- Drug Contamination
- Gene Expression Regulation -- drug effects
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Humans
- Interleukin-17 -- biosynthesis
- Lymphocyte Activation -- drug effects
- Lymphokines -- biosynthesis
- NF-kappa B -- metabolism
- Peptidoglycan -- analysis
- Receptors, Antigen, T-Cell, alpha-beta -- analysis
- Staphylococcus aureus -- chemistry
- Streptococcus pyogenes -- chemistry
- Superantigens -- analysis
- T-Lymphocyte Subsets -- cytology
- Toll-Like Receptor 2 -- agonists
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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