Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma. [electronic resource]
Producer: 20080311Description: 566-73 p. digitalISSN:- 0006-4971
- Abdominal Pain -- chemically induced
- Adolescent
- Adult
- Antineoplastic Agents -- adverse effects
- Arsenic Trioxide
- Arsenicals -- adverse effects
- Child
- Child, Preschool
- Constipation -- chemically induced
- Dermatitis -- drug therapy
- Dose-Response Relationship, Drug
- Female
- Headache -- chemically induced
- Humans
- Hyperglycemia -- chemically induced
- Infusions, Intravenous
- Leukemia, Promyelocytic, Acute -- complications
- Lymphoma -- complications
- Male
- Nausea -- chemically induced
- Oxides -- adverse effects
- Pancreatitis -- chemically induced
- Pneumonia -- chemically induced
- Recurrence
- Time Factors
- Vomiting -- chemically induced
- Water-Electrolyte Balance -- drug effects
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Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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