Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1R-associated kinase, p38, and NF-kappaB in alveolar macrophages stimulated with TLR2 and TLR4 agonists. [electronic resource]
Producer: 20071206Description: 6097-106 p. digitalISSN:- 0022-1767
- Adult
- Cells, Cultured
- Cytokines -- metabolism
- Enzyme Activation
- Gene Expression Regulation
- Humans
- Inflammation Mediators -- metabolism
- Interleukin-1 Receptor-Associated Kinases -- metabolism
- Lipopolysaccharide Receptors -- metabolism
- Lymphocyte Antigen 96 -- metabolism
- Macrophages -- metabolism
- Middle Aged
- NF-kappa B -- metabolism
- Smoking
- Toll-Like Receptor 2 -- agonists
- Toll-Like Receptor 3 -- agonists
- Toll-Like Receptor 4 -- agonists
- Toll-Like Receptors -- agonists
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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