Immunization with DNA topoisomerase I induces autoimmune responses but not scleroderma-like pathologies in mice. [electronic resource]
Producer: 20080201Description: 2243-52 p. digitalISSN:- 0315-162X
- Animals
- Antigens, CD -- immunology
- Antigens, Differentiation -- immunology
- Autoantibodies -- blood
- Autoimmunity
- CTLA-4 Antigen
- DNA Topoisomerases, Type I -- immunology
- Disease Models, Animal
- Female
- Humans
- Immunization
- Immunization, Secondary
- Interleukin-2 Receptor alpha Subunit -- antagonists & inhibitors
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Mice, Mutant Strains
- Recombinant Proteins -- immunology
- Scleroderma, Systemic -- etiology
- T-Lymphocytes -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Intramural
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