Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. [electronic resource]
Producer: 20080129Description: 427-33 p. digitalISSN:- 1742-7843
- Antineoplastic Agents -- administration & dosage
- CREB-Binding Protein -- antagonists & inhibitors
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Curcumin -- administration & dosage
- Dose-Response Relationship, Drug
- E1A-Associated p300 Protein -- antagonists & inhibitors
- Gene Expression Regulation -- drug effects
- Histone Deacetylase 1
- Histone Deacetylase Inhibitors
- Histone Deacetylases
- Humans
- I-kappa B Proteins -- drug effects
- Inhibitory Concentration 50
- Leukemia -- drug therapy
- Leupeptins -- pharmacology
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Receptor, Notch1 -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Transcription Factor RelA -- antagonists & inhibitors
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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