The short hairpin RNA driven by polymerase II suppresses both wild-type and lamivudine-resistant hepatitis B virus strains. [electronic resource]
Producer: 20071206Description: 865-76 p. digitalISSN:- 1359-6535
- Animals
- Antiviral Agents -- pharmacology
- Cell Line, Tumor
- DNA, Viral
- Drug Resistance, Viral
- Gene Expression Regulation, Viral
- Genetic Vectors
- Hepatitis B Surface Antigens -- isolation & purification
- Hepatitis B virus -- drug effects
- Hepatitis B, Chronic -- metabolism
- Humans
- Lamivudine -- pharmacology
- Liver -- cytology
- Mice
- Mice, Inbred BALB C
- Mice, Transgenic
- RNA Interference
- RNA Polymerase II -- metabolism
- RNA, Messenger
- RNA, Small Interfering -- therapeutic use
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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