Concomitant activation of AKT with extracellular-regulated kinase 1/2 occurs independently of PTEN or PIK3CA mutations in endometrial cancer and may be associated with favorable prognosiss. [electronic resource]
Producer: 20071221Description: 1881-8 p. digitalISSN:- 1349-7006
- Adult
- Aged
- Class I Phosphatidylinositol 3-Kinases
- DNA Mutational Analysis
- Endometrial Neoplasms -- enzymology
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Female
- Humans
- Microsatellite Repeats
- Middle Aged
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mutation
- PTEN Phosphohydrolase -- genetics
- Phosphatidylinositol 3-Kinases -- genetics
- Prognosis
- Proto-Oncogene Proteins c-akt -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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