Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. [electronic resource]
Producer: 20080318Description: 213-24 p. digitalISSN:- 0041-008X
- Aryl Hydrocarbon Hydroxylases
- Benzo(a)pyrene -- metabolism
- Biotransformation -- drug effects
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Chromatography, High Pressure Liquid
- Cytochrome P-450 CYP1A1 -- biosynthesis
- Cytochrome P-450 CYP1B1
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dose-Response Relationship, Drug
- Drug Combinations
- Enzyme Induction -- drug effects
- Female
- Fluorenes -- metabolism
- Gas Chromatography-Mass Spectrometry
- Humans
- Microsomes, Liver -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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