Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma. [electronic resource]
Producer: 20071220Description: 5942-51 p. digitalISSN:- 1078-0432
- Animals
- Antineoplastic Agents -- pharmacology
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Line, Tumor
- Cell Survival
- Cell Transformation, Neoplastic
- Enzyme Inhibitors -- pharmacology
- Humans
- Male
- Mesothelioma -- drug therapy
- Mice
- Mice, Nude
- NF-kappa B -- metabolism
- Nitriles -- pharmacology
- Proteasome Inhibitors
- Pyrazines -- pharmacology
- Sulfones -- pharmacology
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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