Effect of Z-360, a novel orally active CCK-2/gastrin receptor antagonist on tumor growth in human pancreatic adenocarcinoma cell lines in vivo and mode of action determinations in vitro. [electronic resource]
Producer: 20080612Description: 883-92 p. digitalISSN:- 0344-5704
- Adenocarcinoma -- drug therapy
- Administration, Oral
- Animals
- Antineoplastic Agents -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Benzodiazepinones -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Deoxycytidine -- administration & dosage
- Disease Models, Animal
- Female
- Gastrins
- Humans
- Mice
- Mice, Nude
- Pancreatic Neoplasms -- drug therapy
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- drug effects
- Receptor, Cholecystokinin B -- antagonists & inhibitors
- Survival Rate
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article
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