Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer. [electronic resource]
Producer: 20090304Description: 53-64 p. digitalISSN:- 1619-7089
- Alpha Particles -- therapeutic use
- Animals
- Bismuth -- chemistry
- Cell Line, Tumor
- Dimerization
- Drug Discovery
- Enzyme Inhibitors -- chemistry
- Female
- Gene Expression Regulation, Neoplastic
- Heterocyclic Compounds, 1-Ring -- chemistry
- Humans
- Kidney -- drug effects
- Ligands
- Mice
- Neoplasm Metastasis
- Ovarian Neoplasms -- genetics
- Peptides -- chemical synthesis
- Polygeline -- pharmacology
- Radioisotopes
- Receptors, Urokinase Plasminogen Activator -- antagonists & inhibitors
- Solubility
- Substrate Specificity
- Tissue Distribution
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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