Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation. [electronic resource]
Producer: 20080107Description: 1199-207 p. digitalISSN:- 1465-7392
- Androstadienes -- pharmacology
- Animals
- Blotting, Western
- Cell Line, Tumor
- Immunohistochemistry
- Immunoprecipitation
- Mutation
- Neurofibromin 2 -- genetics
- Phosphorylation -- drug effects
- Protein Binding
- Protein Kinase Inhibitors -- pharmacology
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Serine -- metabolism
- Threonine -- metabolism
- Ubiquitins -- metabolism
- Wortmannin
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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