Matrix metalloproteinase-9 is up-regulated by CCL21/CCR7 interaction via extracellular signal-regulated kinase-1/2 signaling and is involved in CCL21-driven B-cell chronic lymphocytic leukemia cell invasion and migration. [electronic resource]
Producer: 20080215Description: 383-6 p. digitalISSN:- 0006-4971
- Cell Movement -- physiology
- Chemokine CCL21 -- metabolism
- Collagen
- Drug Combinations
- Endothelium, Vascular -- cytology
- Humans
- Laminin
- Leukemia, Lymphocytic, Chronic, B-Cell -- metabolism
- MAP Kinase Signaling System -- physiology
- Matrix Metalloproteinase 9 -- metabolism
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Neoplasm Invasiveness
- Proteoglycans
- Receptors, CCR7 -- metabolism
- Tumor Cells, Cultured
- Umbilical Veins -- cytology
- Up-Regulation -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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