Enterolactone induces apoptosis in human prostate carcinoma LNCaP cells via a mitochondrial-mediated, caspase-dependent pathway. [electronic resource]
Producer: 20071127Description: 2581-90 p. digitalISSN:- 1535-7163
- 4-Butyrolactone -- analogs & derivatives
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Survival -- drug effects
- Cytochromes c -- metabolism
- Enzyme Activation -- drug effects
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Immunoblotting
- In Situ Nick-End Labeling
- Lignans -- pharmacology
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Phytoestrogens -- pharmacology
- Poly(ADP-ribose) Polymerases -- metabolism
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Tumor Cells, Cultured -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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