Fc optimization of therapeutic antibodies enhances their ability to kill tumor cells in vitro and controls tumor expansion in vivo via low-affinity activating Fcgamma receptors. [electronic resource]
Producer: 20071127Description: 8882-90 p. digitalISSN:- 0008-5472
- Animals
- Antibodies, Monoclonal -- immunology
- Antibody-Dependent Cell Cytotoxicity
- Female
- HT29 Cells
- Humans
- Immunoglobulin G -- immunology
- Lymphoma, B-Cell -- immunology
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Models, Molecular
- Neoplasms -- immunology
- Ovarian Neoplasms -- immunology
- Receptors, IgG -- immunology
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Publication Type: Journal Article
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