Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence. [electronic resource]
Producer: 20071011Description: 2266-72 p. digitalISSN:- 1524-4636
- Animals
- Blood Platelets -- metabolism
- Bone Marrow Transplantation
- Cell Line, Tumor
- Cell Shape
- Genes, Reporter
- Genetic Vectors
- Green Fluorescent Proteins
- Hematopoietic Stem Cells -- metabolism
- Humans
- Lentivirus -- genetics
- Megakaryocytes -- metabolism
- Mice
- Platelet Adhesiveness
- Platelet Glycoprotein GPIIb-IIIa Complex -- metabolism
- Platelet Glycoprotein GPIb-IX Complex -- genetics
- Platelet Membrane Glycoprotein IIb -- genetics
- Promoter Regions, Genetic
- RNA Interference
- RNA Polymerase III -- genetics
- RNA, Small Interfering -- genetics
- Signal Transduction
- Talin -- genetics
- Thrombopoiesis
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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