Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity. [electronic resource]
Producer: 19920218Description: 57-65 p. digitalISSN:- 0264-6021
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Western
- Cell Division -- drug effects
- Chromatography, Gel
- Chromatography, Ion Exchange
- Cloning, Molecular -- methods
- Electrophoresis, Polyacrylamide Gel
- Endopeptidases -- metabolism
- Escherichia coli -- genetics
- Genes, Synthetic
- Humans
- Inositol Phosphates -- metabolism
- Mice
- Molecular Sequence Data
- Molecular Weight
- Mutagenesis, Site-Directed
- Plasmids
- Platelet-Derived Growth Factor -- genetics
- Recombinant Proteins -- isolation & purification
- Restriction Mapping
- Saccharomyces cerevisiae -- genetics
- Structure-Activity Relationship
- Transcription, Genetic
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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