Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome. [electronic resource]
Producer: 20080109Description: 270-9 p. digitalISSN:- 1044-7431
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Apoptosis -- physiology
- Cell Differentiation -- drug effects
- Cell Line, Transformed
- Gene Expression Regulation -- physiology
- Hippocampus -- cytology
- Humans
- Immunoprecipitation
- Inclusion Bodies -- pathology
- Neurons -- metabolism
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Protein-Tyrosine Kinases -- metabolism
- Serum -- metabolism
- Time Factors
- Transfection
- tau Proteins -- genetics
- Dyrk Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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