LCAT can rescue the abnormal phenotype produced by the natural ApoA-I mutations (Leu141Arg)Pisa and (Leu159Arg)FIN. [electronic resource]
Producer: 20071106Description: 10713-21 p. digitalISSN:- 0006-2960
- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Transporters -- metabolism
- Adenoviridae Infections
- Animals
- Apolipoprotein A-I -- blood
- Arginine -- genetics
- Cell Line, Tumor
- Cholesterol -- metabolism
- Enzyme Activation
- Gene Expression Regulation
- Humans
- Leucine -- genetics
- Lipids -- blood
- Lipoproteins, HDL -- metabolism
- Liver -- metabolism
- Mice
- Mice, Inbred C57BL
- Models, Biological
- Molecular Weight
- Mutant Proteins -- isolation & purification
- Mutation -- genetics
- Phenotype
- Phosphatidylcholine-Sterol O-Acyltransferase -- metabolism
- RNA, Messenger -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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