Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome. [electronic resource]
Producer: 20071019Description: 556-64 p. digitalISSN:- 0896-6273
- Animals
- Animals, Genetically Modified
- DNA-Binding Proteins -- genetics
- Disease Models, Animal
- Drosophila
- Drosophila Proteins -- genetics
- Eye -- pathology
- Fragile X Mental Retardation Protein -- genetics
- Fragile X Syndrome -- complications
- Green Fluorescent Proteins -- genetics
- HSP70 Heat-Shock Proteins -- metabolism
- Heterogeneous-Nuclear Ribonucleoprotein Group A-B -- genetics
- Humans
- Immunoprecipitation -- methods
- Mice
- Microscopy, Electron, Scanning -- methods
- Nerve Degeneration -- genetics
- Nerve Tissue Proteins
- RNA-Binding Proteins -- genetics
- Transcription Factors -- genetics
- Trinucleotide Repeat Expansion -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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