Dihydrodiol dehydrogenases regulate the generation of reactive oxygen species and the development of cisplatin resistance in human ovarian carcinoma cells. [electronic resource]
Producer: 20080619Description: 979-87 p. digitalISSN:- 0344-5704
- Alcohol Oxidoreductases -- biosynthesis
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Cell Line, Tumor
- Cisplatin -- pharmacology
- Clone Cells
- Drug Resistance, Neoplasm
- Enzyme Induction -- drug effects
- Esterases -- biosynthesis
- Female
- Heme Oxygenase (Decyclizing) -- biosynthesis
- Humans
- Hydrogen Peroxide -- pharmacology
- Isoenzymes -- biosynthesis
- Ovarian Neoplasms -- drug therapy
- Oxidative Stress -- drug effects
- RNA, Small Interfering -- pharmacology
- Reactive Oxygen Species -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- tert-Butylhydroperoxide -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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