Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. [electronic resource]
Producer: 20071127Description: 1065-7 p. digitalISSN:- 1061-4036
- 3' Untranslated Regions -- genetics
- Endosomes -- metabolism
- Exodeoxyribonucleases -- chemistry
- Frameshift Mutation
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Green Fluorescent Proteins -- genetics
- HeLa Cells
- Humans
- Lupus Erythematosus, Cutaneous -- enzymology
- Mutation
- Mutation, Missense
- Phosphoproteins -- chemistry
- Protein Structure, Tertiary
- Recombinant Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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