Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL. [electronic resource]
Producer: 20080206Description: 490-8 p. digitalISSN:- 1476-5594
- Apoptosis -- drug effects
- Azacitidine -- analogs & derivatives
- Cell Line, Tumor
- DNA (Cytosine-5-)-Methyltransferase 1
- DNA (Cytosine-5-)-Methyltransferases -- antagonists & inhibitors
- DNA Methylation -- drug effects
- Decitabine
- Drug Evaluation, Preclinical
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Silencing -- drug effects
- Humans
- Interferons -- therapeutic use
- Melanoma -- drug therapy
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- genetics
- TNF-Related Apoptosis-Inducing Ligand -- therapeutic use
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
There are no comments on this title.
Log in to your account to post a comment.