Evidence for the facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Basic properties and specificity for polyglutamate chain length. [electronic resource]
Producer: 19910724Description: 11732-7 p. digitalISSN:- 0021-9258
- Animals
- Biological Transport
- Cations
- Cell Line
- Lysosomes -- metabolism
- Magnesium -- metabolism
- Methotrexate -- analogs & derivatives
- Mice
- Osmolar Concentration
- Polyglutamic Acid -- analogs & derivatives
- Potassium -- metabolism
- Substrate Specificity
- Tumor Cells, Cultured
- beta-N-Acetylhexosaminidases -- analysis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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