2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2. [electronic resource]
Producer: 20070828Description: 1503-9 p. digitalISSN:- 1055-9965
- Acetylation
- Acetyltransferases
- Animals
- Arylamine N-Acetyltransferase -- genetics
- CHO Cells -- drug effects
- Carcinogens -- toxicity
- Chromatography, High Pressure Liquid
- Cricetinae
- Cricetulus
- Cytochrome P-450 CYP1A1 -- genetics
- DNA Adducts
- DNA Damage
- DNA Repair -- genetics
- Gene Expression Regulation, Enzymologic -- physiology
- Humans
- Mutagenesis -- genetics
- Mutation -- genetics
- Quinoxalines -- toxicity
- Tandem Mass Spectrometry
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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