Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants. [electronic resource]
Producer: 20071107Description: 238-47 p. digitalISSN:- 0022-3042
- Amino Acid Substitution
- Animals
- Cell Line
- Enzyme Activation -- genetics
- GTP Phosphohydrolases -- genetics
- Guanosine Triphosphate -- metabolism
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Mice
- Mice, Transgenic
- Mutation
- Organ Specificity
- Parkinson Disease -- enzymology
- Protein Serine-Threonine Kinases -- genetics
- Protein Structure, Tertiary -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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