Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man. [electronic resource]
Producer: 20071031Description: 111-8 p. digitalISSN:- 0300-483X
- 20-Hydroxysteroid Dehydrogenases -- chemistry
- Alcohol Oxidoreductases -- metabolism
- Aldehyde Reductase
- Aldo-Keto Reductases
- Antineoplastic Agents -- chemistry
- Catalysis
- Cytosol -- enzymology
- Electrophoresis, Polyacrylamide Gel
- Ethanolamines -- chemistry
- Humans
- Hydroxysteroid Dehydrogenases -- chemistry
- Inactivation, Metabolic
- Isoquinolines -- chemistry
- Liver -- cytology
- Molecular Structure
- Oxidation-Reduction
- Oxidoreductases -- chemistry
- Stereoisomerism
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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