Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis. [electronic resource]
Producer: 20080102Description: 2194-202 p. digitalISSN:- 0364-3190
- Apoptosis -- drug effects
- Brain Neoplasms -- drug therapy
- Cell Survival -- drug effects
- Cytochromes c -- metabolism
- Cytosol -- drug effects
- Genes, Reporter -- drug effects
- Glioblastoma -- drug therapy
- Humans
- Interferon-gamma -- pharmacology
- Luciferases -- genetics
- NF-kappa B -- genetics
- Nerve Tissue Proteins -- biosynthesis
- PTEN Phosphohydrolase -- genetics
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Recombinant Proteins
- Signal Transduction -- drug effects
- Transfection
- Tretinoin -- pharmacology
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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