Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of bile acid synthesis. [electronic resource]
Producer: 19910531Description: 2149-58 p. digitalISSN:- 0022-2275
- Acyl Coenzyme A -- antagonists & inhibitors
- Animals
- Bile Acids and Salts -- biosynthesis
- Cholesterol -- metabolism
- Cholesterol 7-alpha-Hydroxylase -- metabolism
- Dehydrocholesterols -- metabolism
- Down-Regulation
- Kinetics
- Liver -- enzymology
- Male
- Mevalonic Acid -- analogs & derivatives
- Rats
- Rats, Inbred Strains
- trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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