Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis. [electronic resource]
Producer: 20071105Description: 667-75 p. digitalISSN:- 1073-449X
- Animals
- Benzoquinones -- pharmacology
- Chemokines -- metabolism
- Cytokines -- metabolism
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Inflammation
- Inflammation Mediators -- metabolism
- Lactams, Macrocyclic -- pharmacology
- Lung -- metabolism
- Macrolides -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- NF-kappa B -- metabolism
- Nitrates -- metabolism
- Nitric Oxide Synthase Type II -- metabolism
- Nitrites -- metabolism
- Peroxidase -- metabolism
- Respiratory Distress Syndrome -- etiology
- Sepsis -- complications
- Survival Rate
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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