Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury. [electronic resource]
Producer: 20071129Description: 1132-46 p. digitalISSN:- 0897-7151
- Animals
- Atorvastatin
- Brain Injuries -- drug therapy
- Cell Proliferation -- drug effects
- Dentate Gyrus -- cytology
- Dose-Response Relationship, Drug
- Heptanoic Acids -- pharmacology
- Hippocampus -- drug effects
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Male
- Maze Learning -- drug effects
- Memory Disorders -- drug therapy
- Neovascularization, Physiologic -- drug effects
- Nerve Degeneration -- drug therapy
- Nerve Regeneration -- drug effects
- Neuronal Plasticity -- drug effects
- Neurons -- drug effects
- Neuroprotective Agents -- pharmacology
- Pyrroles -- pharmacology
- Rats
- Rats, Wistar
- Recovery of Function -- drug effects
- Simvastatin -- pharmacology
- Stem Cells -- drug effects
- Treatment Outcome
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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