Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver. [electronic resource]
Producer: 20071106Description: 2334-41 p. digitalISSN:- 0006-4971
- Adenoviridae -- genetics
- Animals
- Antibodies, Monoclonal -- immunology
- Antibodies, Monoclonal, Humanized
- B-Lymphocytes -- metabolism
- CD4-Positive T-Lymphocytes -- cytology
- Capsid Proteins -- genetics
- Daclizumab
- Factor IX -- genetics
- Gene Expression
- Gene Transfer Techniques
- Genetic Therapy
- Genetic Vectors -- genetics
- Humans
- Immune Tolerance -- immunology
- Immunoglobulin G -- pharmacology
- Immunosuppressive Agents -- pharmacology
- Liver -- immunology
- Macaca mulatta -- genetics
- Male
- Models, Animal
- Mycophenolic Acid -- analogs & derivatives
- Receptors, Interleukin-2 -- immunology
- Sirolimus -- pharmacology
- Transgenes -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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