Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis. [electronic resource]
Producer: 20071015Description: 3618-26 p. digitalISSN:- 0022-2623
- Actins -- antagonists & inhibitors
- Adult
- Animals
- Anti-Inflammatory Agents -- chemical synthesis
- Chemotaxis, Leukocyte
- Humans
- Interleukin-8 -- pharmacology
- Male
- Mice
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Neutrophils -- drug effects
- Peritoneal Cavity -- cytology
- Peritonitis -- pathology
- Phenylurea Compounds -- chemical synthesis
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- metabolism
- Pseudopodia -- drug effects
- Pyrazoles -- chemical synthesis
- Receptors, Interleukin-8A -- metabolism
- Receptors, Interleukin-8B -- metabolism
- Structure-Activity Relationship
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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