Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia. [electronic resource]
Producer: 20071108Description: 222-34 p. digitalISSN:- 0042-6822
- AIDS Dementia Complex -- pathology
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- metabolism
- Brain -- pathology
- CD4 Antigens -- metabolism
- Cell Line
- Dogs
- Genetic Variation
- Glycosylation
- HIV Envelope Protein gp120 -- chemistry
- HIV-1 -- pathogenicity
- Humans
- Macrophages -- virology
- Models, Molecular
- Molecular Sequence Data
- Neutralization Tests
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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