Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. [electronic resource]
Producer: 20071029Description: 25726-36 p. digitalISSN:- 0021-9258
- Animals
- Binding Sites -- physiology
- Crystallography, X-Ray
- Dimerization
- Humans
- Isoxazoles -- chemistry
- Kainic Acid -- analogs & derivatives
- Ligands
- Organophosphonates -- chemistry
- Protein Binding -- physiology
- Protein Structure, Tertiary -- physiology
- Receptors, AMPA -- agonists
- Receptors, Kainic Acid -- agonists
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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