Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy. [electronic resource]
Producer: 20070801Description: 7520-4 p. digitalISSN:- 0022-1767
- Alleles
- Amino Acid Substitution
- Cell Membrane -- chemistry
- Cells, Cultured
- Gene Frequency
- Homozygote
- Humans
- Isoleucine -- chemistry
- Leprosy -- genetics
- Monocytes -- immunology
- Mycobacterium leprae -- immunology
- Polymorphism, Single Nucleotide
- Protein Transport
- Serine -- chemistry
- Toll-Like Receptor 1 -- analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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