Metabolism of central neurotransmitters during development of tolerance to the anticonvulsant effect of clonazepam and of physical dependence on the drug in dogs. [electronic resource]
Producer: 19901227Description: 172-82 p. digitalISSN:- 0003-9780
- 6-Ketoprostaglandin F1 alpha -- cerebrospinal fluid
- Animals
- Anticonvulsants
- Brain Chemistry -- drug effects
- Clonazepam -- pharmacology
- Dinoprostone -- cerebrospinal fluid
- Dogs
- Drug Tolerance
- Female
- Homovanillic Acid -- cerebrospinal fluid
- Hydroxyindoleacetic Acid -- chemical synthesis
- Injections, Intraventricular
- Male
- Neurotransmitter Agents -- metabolism
- Prostaglandins -- biosynthesis
- Sleep -- drug effects
- Substance-Related Disorders -- physiopathology
- Thromboxane B2 -- cerebrospinal fluid
- gamma-Aminobutyric Acid -- cerebrospinal fluid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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