A cell model system to study regulation of phosphotidylinositol 3-kinase and protein kinase B activity by cytokines/growth factors produced by type I collagen stimulated immune cells from patients with systemic sclerosis. [electronic resource]
Producer: 20070912Description: 1181-6 p. digitalISSN:- 0006-3002
- Arthritis, Rheumatoid -- blood
- Case-Control Studies
- Cell Line
- Cells, Cultured
- Collagen Type I -- pharmacology
- Culture Media -- metabolism
- Cytokines -- pharmacology
- Enzyme-Linked Immunosorbent Assay
- Humans
- Intercellular Signaling Peptides and Proteins -- pharmacology
- Leukocytes, Mononuclear -- cytology
- Lupus Erythematosus, Systemic -- blood
- Megakaryocytes -- cytology
- Nitric Oxide Synthase -- metabolism
- Osteoarthritis -- blood
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-akt -- metabolism
- Scleroderma, Systemic -- metabolism
- Tyrosine -- analogs & derivatives
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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